First Aired: November 27, 2005

Plot: After finding an old family picture showing a brother she never knew she had, Lois sets out to find her unknown sibling. Meanwhile, after a physical with Dr. Hartman, Peter realizes that he is fat and decides to fight for fat people’s rights by founding a fat people’s club. Lois finds her brother Patrick in a mental hospital, where he’s been locked up since childhood and thinks he has a wife whom no one but him can see. After talking with him for a few minutes, she decides to take him home. There, Patrick explains that he was locked up because, as an infant, he walked in on their mother having an affair with Jackie Gleason, which emotionally scarred him. Unfortunately, Peter’s physical appearance and manners (as well as a Jackie Gleason Honeymooners outfit he likes to wear) bring back the trauma from that event, and Patrick goes on a killing spree, strangling fat men.

Lois is reluctant to believe that Patrick is the Strangler, even with obvious signs (pictures of Pat strangling fat guys, a dead fat guy in his room, a half-dead fat guy in his room, and others). Finally, she gives in and believes everything, and it’s up to her and Brian to save Peter from being strangled. They arrive just in time as Patrick is strangling Peter. Lois threatens to “kill” his imaginary wife, distracting Patrick. Brian takes the opportunity to hit Peter with a rock for “rolling up the damn window when I tried to jump in the General Lee.” By the next day, Patrick is brought back to the mental hospital.